Anthropology and Human Genetics
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Comparative Genomics

Our research focuses on Comparative and Population Genomics. The goal is to disentangle selective and neutral forces that shape genomes. Recently, we focused on the analysis and integration of single cell transcriptomes. Overall, we seek to apply the principles of genome evolution to

  • Cancer Evolution (SFB 1243)

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    Most AML-patients have at least one mutation in an epigenetic modifier gene. Here, we want to investigate in how far those mutations act by inducing an epigenetic mutator phenotype. more

  • Computational Tools

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    We develop tools and pipelines for single cell RNA-seq analysis. more

  • Regulatory Evolution

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    We want to understand how regulatory elements in the genome evolve. To this end we combine genetic, epigenetic and gene expression data and analyse them from an evolutionary perspective. more

  • Population Genomics

    With genome scale re-sequencing data allow us to tackle new questions f.e. the detection of life history traits such as sex biases in mating and revisit older questions such as searching for selective sweeps. more