Anthropology and Human Genetics
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powsimR: Power analysis for bulk and single cell RNA-seq experiments

by B. Vieth, C. Ziegenhain, S. Parekh, W. Enard and I. Hellmann

11.07.2017

Abstract

Power analysis is essential to optimize the design of RNA-seq experiments and to assess and compare the power to detect differentially expressed genes in RNA-seq data. PowsimR is a flexible tool to simulate and evaluate differential expression from bulk and especially single-cell RNA-seq data making it suitable for a priori and posterior power analyses.

PowsimR is freely available at github!

Bioinformatics

powsim_schematic - 1